EARA | Patient Discovery

Through direct engagement and open dialogue, patients gain first-hand insight into how research leads to new treatments that improve lives, while researchers gain first-hand knowledge of patients’ lived experiences, helping to increase the relevance and quality of biomedical research.

A shared journey in research

The Patient Discovery Project is a core EARA initiative designed to strengthen dialogue between patients, patient organisations and the biomedical research community. It aligns closely with EARA’s mission to provide accurate, evidence-based information about the role of animal research and to promote openness, transparency and trust in science.

By inviting patients and their families into research environments, the project offers a clear and honest view of how biomedical research works, why animals are still needed when no viable alternatives exist, and how high ethical and welfare standards are applied. This helps increase the relevance of research, align scientific work with societal expectations and real-world needs and ultimately strengthen the quality and impact of biomedical research.

Benefits for participants

A deeper understanding of the research process and its ethical framework

Direct interaction with scientists, clinicians and animal care staff

The ability to act as informed voices within their communities and in public debate

Benefits for researchers

First-hand insight into patients’ lived experiences, priorities and unmet needs

Increased research relevance through closer alignment with societal expectations

Improved research quality by integrating patient perspectives into study design and communication

Benefits for organisations

Stronger trust and transparency between institutions and the public

Enhanced institutional openness and credibility around the use of animals in research

How can you join the Patient Discovery Project?

EARA is expanding the Patient Discovery Project across Europe, building on successful Discovery Days held in the Netherlands, Portugal, Belgium and Spain. The project offers a structured way to connect patients, researchers and institutions through transparent, meaningful engagement.

You may be a good fit if you:

Are a researcher or research institution involved in basic or applied biomedical research
Work with animals and/or new approach methodologies (NAMs) to answer scientific or medical questions
Are committed to transparency and openness about the use of animals and NAMs in research, including ethical standards and welfare practices
Are interested in strengthening dialogue with patients and the public
Collaborate with a patient organisation or advocacy group

EARA offers:

Support in designing and delivering a Patient Discovery Day
Help connecting researchers with relevant patient organisations
Guidance on transparent communication around research, ethics and animal welfare
Visibility through EARA’s European network and communication channels

The EARA Patient Discovery Project is an innovative and crucial step in bridging the gap between medical research and patients. By providing a clear and honest understanding of why animal research remains essential to developing new treatments and scientific progress, this project fosters informed dialogue and strengthens vital trust between researchers and those who stand to benefit most—patients and their families.

Kirk Leech, EARA Executive Director

Contact EARA's Patient Engagement Officer if you are interested in hosting a Discovery Day or joining the Patient Discovery Project.

What are Discovery Days?

During a Discovery Day, participants attend short talks by researchers, visit laboratories and research facilities, and observe different research methods in practice. The day also includes open discussions and Q&A sessions, allowing participants to ask questions, share experiences and engage directly with the scientists.

Across all past Discovery Days, a common theme has emerged: informed engagement builds trust. Facility visits, transparent discussions and direct observation help demystify research, dispel misconceptions and highlight the care, expertise and responsibility that underpin animal research. Patients become active contributors to the research ecosystem — they become important disseminators of information, able to shape public opinion, influence policy and guide research priorities.

Patients’ voices ensure that biomedical research remains focused on what truly matters - improving lives, without compromising the highest scientific standards and animal welfare.

Past Discovery Days

2026

EARA and EARA member Champalimaud Foundation hosted a Patient Discovery Day in Portugal in collaboration with Young Parkies Portugal, bringing together researchers and people living with early onset Parkinson’s disease to explore how biomedical research, including the ethical use of animals, contributes to understanding disease mechanisms and developing future therapies.

The programme included:
- A guided visit to the animal research facilities, highlighting housing standards, welfare monitoring and the role of the Animal Welfare Officer
- Live demonstrations of behavioural tests used to assess movement alterations associated with Parkinson’s disease, including explanations on how animals, particularly mice, are used to study disease progression
- Open discussions between participants and scientists, connecting lived experiences with ongoing research efforts and priorities

The day concluded with informal exchanges between researchers and participants, strengthening mutual understanding and reinforcing transparency, trust and collaboration between people living with Parkinson’s and the scientific community.

After the visit:
- 73% said their views on animal research changed
- 100% believed researchers prioritise animal welfare
- 100% recognised the medical impact of animal research
- 82% said they would not support slowing medical progress to reduce animal use
- 100% supported transparency about animal research

2025

In October 2025, EARA and KU Leuven, EARA member in Belgium, hosted a Patient Discovery Day in collaboration with the European Federation of Neurological Associations (EFNA), bringing together patient representatives from across Europe to explore the role of animal research in neurodegenerative disease research.

The programme included:
- Presentations on research about brain diseases, including neurodegeneration, animal research regulation and welfare
- Visits to research groups using fruit flies, mice and macaque monkeys at different stages of preclinical research
- Visit to imaging facilities developing biomarkers for diagnosis and therapy monitoring

The day concluded with an open Q&A session, reinforcing transparency, trust and dialogue between patients and researchers.

After the visit:
- 75% participants said their views on animal research changed
- 75% reported confidence in animal welfare practices
- 100% recognised the medical impact
- 100% supported institutional transparency

2024

People living with diabetes together with representatives of the Portuguese Diabetic Association/APDP, visited the NOVA Medical School, EARA member in Lisbon, to experience at first hand the research studies on diabetes at NOVA and particularly the crucial role of animals, such as mice and rats, in understanding the disease and developing new therapies and future treatments. Participants heard about the ongoing studies on type 2 diabetes and engaged in a discussion with researchers and physicians where they shared their concerns and experiences about the disease, contributing new perspectives to the research process with insights that researchers might not be aware of.

Participants:
- Learned how mice and rats are used to study blood glucose regulation, memory changes and metabolic processes associated with diabetes
- Observed blood glucose monitoring procedures comparable to human finger-prick tests
- Observed more advanced procedures, including surgery under full anaesthesia, which were explained in detail, with emphasis on animal welfare, pain management and ethical oversight
- Discussed research questions directly with scientists and physicians, sharing personal experiences that informed research perspectives

After the visit:
- 83% highlighted the high relevance and quality of the visit
- 92% of participants reported their knowledge of animal research increased
- 92% of participants felt comfort and trust
- 92% of participants strongly supported public understanding of animal research

2023

The Patient Discovery Project was launched in the Netherlands in 2023, at the EARA member Radboud University, where participants learned about the vital contribution of mice and rats in studying Parkinson’s disease.

Participants took part in the Toolkit to Understand Parkinson’s Disease, learning about the various research methods using mice and rats at Radboud University Medical Centre, followed by a visit to different research facilities.

The programme included visits to:
- Cell culture laboratories exploring neuronal and stem cell techniques
- Biochemical laboratories analysing Parkinson’s patients’ samples
- Animal facilities showcasing behavioural and imaging studies in mice and rats

After the visit:
- 90% of participants reported high satisfaction
- 75% said they had an improved understanding of Parkinson’s research

What are our major achievements so far?

Increased patients’ knowledge and understanding of how animals and NAMs are used together across the research process
Greater trust in researchers and institutions, particularly regarding animal welfare standards and responsible selection of experimental methods and models
Strong appreciation for first-hand access to research facilities that are not usually accessible to the public
Positive impact on researchers, who report improved understanding of patients’ perspectives
Creation of a growing, engaged community of informed patients, laying the foundation for a Patient Advocacy Network, to move from one-off Discovery Days to sustained involvement in dialogue, advocacy and contributions to research and policy at national and European levels

Testemonials

It feels like a privilege that we were able to get a glimpse into Radboud University and its animal facility. All locations, but especially the last one, made a significant impression.

Janneke den Ouden, participant of the Discovery Day at Radboud University Medical Centre (translation from Dutch)

It was a great experience to see how interested the patients were in our fundamental research and to give fundamental researchers a face. I am sure that this has contributed to decreasing the distance between bench and bed.

Marijn Kuijpers, assistant professor at Radboud University (translation from Dutch)

I did not imagine that there were so many research lines in diabetes and the passion of the researchers working with animals really surprised me.

António Coelho, participant of the Discovery Day at Nova Medical School (translation from Portuguese)

I have always thought scientists made sure animals were not suffering during experiments, but I was greatly surprised with the extreme amount of care from the researchers towards the animals.

José Duarte, participant of the Discovery Day at Nova Medical School (translation from Portuguese)

The patients surprised me... I was not expecting them to be so well informed and to ask such complex questions.

Sílvia Conde, researcher from Nova Medical School (translation from Portuguese)

This research I was able to witness is not separated from patients. And the animals are well taken care of.

Manuela Godinho, participant of the Discovery Day at Nova Medical School (translation from Portuguese)

Grateful for the opportunity to visit the research labs at KU Leuven this week. What stood out most wasn’t just the cutting-edge science - it was the care, transparency, and ethical commitment woven into every corner of their work (…) KU Leuven sets a powerful example of how science and humanity can walk hand in hand. Their dedication to the 3Rs and open dialogue around animal welfare left a lasting impression.

Jagdeep Aujla, Dopamine Warriors Boxing Club, participant with Parkinson’s disease during the Discovery Day at KU Leuven

Before this visit, I had a very negative opinion about animal research. What surprised me most was seeing the humane treatment of the animals. I leave with a completely different perspective.

Beatriz del Barrio, AMACOP, participant with long Covid during the Discovery Day at CNB-CSIC (translation from Spanish)

Studies tell us there are hundreds of symptoms, but patients help us understand which ones are truly dominant in real life. That allows us to prioritise the right questions and reconsider what we analyse in our animal models based on their observations

Isabel Sola, researcher from CNB-CSIC and co-head of the CNB-CSIC Coronavirus Research Group (translation from Spanish)

You could see the change in the participants like coming in with reservations and maybe sceptical, or maybe even negative feelings towards our research, and then leaving with understanding on why this is necessary.

Jinte Middeldorp, researcher from the Biomedical Primate Research Center (during the webinar)

I was very surprised to see the really good living conditions, that the monkeys live in groups and they actually have a better space and surroundings than in many zoos.

Monique Bosman, participant of both Discovery Days hosted in the Netherlands (during the webinar)

With all the regulatory compliance we have in Europe, we can be sure that animal experiments are conducted responsibly and only when necessary. That’s vital for building confidence among patients like us, who are the end users of this work.

António Coelho, participant of the Discovery Day at Nova Medical School (during the webinar)

The visit to the animal facility, together with the explanation of some ongoing research, helped us better understand the challenges, demands and complexity behind the work carried out there. Seeing the rigour of the research up close did not give us promises, but rather a certainty: that there is a genuine commitment to finding solutions. For those living with early-onset Parkinson’s, this does not solve the present. But it changes how we face the future, giving us greater hope.

Martine Pinheiro, participant of the Discovery Day at Champalimaud Foundation (translated from portuguese)

Sharing our work in animal research is always rewarding, but this visit was especially meaningful. Welcoming people living with Parkinson’s and connecting them with research related to their condition made the experience more personal and impactful for everyone involved.

Patient Discovery