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A US strategy for developing a vaccine for HIV, based on training the immune system, is providing hope Currently there is no vaccine that can prevent or treat HIV and the main challenge lies with the fact s genome mutates very rapidly, making it difficult to generate an immune response against it with a vaccine

to support the biomedical sector over the growing shortage of purpose-bred macaque monkeys, used in Covid Kirk Leech, EARA executive director, said: “Monkeys play a critical role in the development of vaccines , such as those for Covid-19, and urgent international co-operation is needed to lift the ban.” -19 vaccines, and in April 2020 the European Medicines Agency and U.S. the Tulane National Research Centre, USA showing the primate facilities and how they play a role in Covid

US researchers have confirmed the importance of using rhesus macaque monkeys as models in Covid-19 research The results, published in Nature Microbiology, show the value of rhesus macaques in particular for Covid -19 vaccine research. Baboons can also provide more detailed information about the potential effects of Covid-19 on other diseases information moving forward as we delve deeper into understanding the disease and targets for therapeutics and vaccines

(NZAVS) NZAVS supports their initial claim by citing a new experimental Covid-19 vaccine developed by Their experimental vaccine is based on mRNA, a molecule which carries information to make proteins, whereas typically vaccines contain the dead or weakened virus. ‘Testing vaccines and medicines without taking the time to fully understand safety risks [through animal and if the Moderna vaccine is successful it will again be thanks in some small part to the use of animals

US researchers have used mice to develop an ‘inverse vaccine’ with the potential to combat autoimmune And while traditional vaccines target molecules from invasive viruses and bacteria, this new ‘inverse vaccine’ approach focuses on erasing the immune system’s memory and targeting of its own cells. ability, to label molecules from ageing cells as non-threatening to the immune system, to develop a vaccine In a mice autoimmune disease model, this ‘inverse vaccine’ encouraged the immune system to recognise

Following animal studies, an experimental vaccine for chlamydia has been shown to be safe and able to There is currently no vaccine, which can give long-term protection and immunity against infection. by Imperial College London, UK, and the Statens Serum Institut, Denmark – which also developed the vaccine demonstrated that CTH522 gave protection to the animals, while monkeys were used to identify the best way to vaccinate The next step will be to conduct further trials to investigate whether the vaccine can fight infection

US researchers have developed a ‘vaccine’ that successfully reduced allergic reactions in mice with asthma Current vaccines ( allergy immunotherapies ) require repeated exposure to allergens, which can risk severe In allergic mice, the vaccine reduced airway inflammation and mucus production—key symptoms of asthma—for The research team is now exploring similar vaccines for food allergies, including peanut and milk.

Research from the Netherlands, using mice, has revealed that a new type of mRNA vaccine is safe to use Self-amplifying mRNA (SAM) vaccines are an advanced form of mRNA vaccine that not only contain the genetic code for a viral protein to be produced, like the mRNA vaccine used for immunising against Covid-19, To test this, researchers at EARA member Wageningen University injected these SAM vaccines into healthy These findings suggest that SAM vaccines can be a key tool in developing new mRNA vaccines that promote

A project to deliver mRNA vaccines in oral form will not go ahead following an early-stage study in mice BioNTech, the German company that has successfully developed mRNA vaccines for Covid-19, has been looking for a way to deliver mRNA vaccines orally since last year, using a technology developed by Matinas Biopharma To test whether the vaccine worked in mice, Matinas used a formulation to ‘handle the complexity and A recent PLOS article has looked at the progress of other intranasal and oral vaccines for Covid-19,

A team from the Pirbright Institute, UK, are to test new vaccines for COVID-19 using pigs as an animal The vaccines, developed at the University of Oxford, UK, contain the protein from COVID-19 which results The team will vaccinate pigs and then measure the level of protective antibodies produced to assess the vaccine’s ability to block COVID-19 from causing disease. similar to that of humans and these tests will demonstrate the safety and effectiveness of the new vaccine

A vaccine for treating a bacterial infection that commonly causes diarrhoea, may help babies grow faster A study at Oregon Health & Science University (OHSU), looked at the effects of HydroVax vaccine, which Researchers found that vaccinating pregnant monkeys and their babies (which naturally harbour campylobacter ) resulted in the babies being taller than those that had not been vaccinated, relative to their age. prevent bacterial diarrhoea in babies and to enable more children to grow into healthy adults, and this vaccine

expert group recommendation that calls for an end to the use of animals in antibody research, including Covid stating that the use of animal-derived antibodies for research and treatment of diseases, including Covid In response, the EARA/EFPIA report noted that many of the current front-running antibody drugs for Covid The report observed: “At a time when the world is depending on biomedical researchers to find a vaccine importance in the global struggle to better understand and rapidly advance therapeutics to combat Covid