Researchers in Belgium have discovered, in a mouse study, that a gene mutation long linked to psoriasis also affects gut function. Psoriasis is a chronic, non-contagious skin condition caused by an overactive immune system. It leads to red, scaly patches and skin inflammation and may affect other organs, including the gut.  

Researchers in the US have identified a previously unknown brain circuit that controls how mice respond to sudden threats and recover from fear. 

Researchers in the US have developed lab-grown kidneys (organoids) that, for the first time, could produce urine when transplanted into mice.  

Researchers in Germany and Austria have discovered that the acidic environment inside tumours plays a key role in promoting cancer survival and growth.  

Researchers in Sweden have discovered what changes in the brain of mice that unlock the so-called maternal aggression. 

Researchers in the US have found that amyloid beta, a hallmark in Alzheimer’s, can strengthen immune responses and reduce tumour growth in mice. 

The 2025 Nobel Prize in Physiology or Medicine was awarded to three researchers — Shimon Sakaguchi, Mary E. Brunkow and Fred Ramsdell — for discovering how the immune system is kept in check, based on studies in mice.

A team based in the UK and Italy has developed a method to monitor a key brain alteration found in Alzheimer’s disease in the brain of living, freely moving mice using optic fibres. 

Researchers in Portugal and France discovered that the spinal cord plays a crucial role in sexual behaviour in mice and rats, opening new ways for treating sexual dysfunction in humans.

A prominent gene therapy company has announced a groundbreaking therapy for Huntington’s disease that slowed disease progression by 75% in human clinical trials.

Researchers in France have discovered that stress during pregnancy can make the progeny susceptible to develop eczema, in a study using mice. 

Researchers in Japan have tested a new drug that provides powerful pain relief in mice and monkeys, without the dangers of opioids.  

US scientists have developed a new method that turns the mouse scalp transparent, making it possible to image the living brain during its development. 

Researchers in Germany have found, in a study using mice and humans, that loss of the sense of smell can be one of the earliest signs of Alzheimer’s, before cognitive impairment. 

Researchers in Israel are preparing to test the first-ever implantation of patients’ own spinal cord cells to restore mobility in paralysed individuals — a breakthrough made possible by foundational experiments in mice. 

Researchers from Germany and the US have discovered how the breast cancer drug tamoxifen can increase the risk of tumours in the uterus, in a study using mice. 

Researchers in the US used artificial intelligence to discover two new antibiotics that can clear superbugs in mice infected with MRSA and drug-resistant gonorrhoea.

Spanish researchers captured the first video of a human embryo implanting in a uterus, which could help improve understanding of the natural process and improve fertility and assisted reproduction techniques. 

Researchers in Canada have discovered why a group of childhood brain cancers are resistant to radiation therapy in a study using mice. 

Researchers in the US found that lithium, a metal naturally present in the brain, could protect and reverse symptoms of Alzheimer's disease, in a study using human samples and mice.