Device to control epileptic seizures works in rats

Researchers using rats have developed a treatment for epilepsy using a device implanted into the brain.


The protein-secreting device reduced seizures by 93 percent in three months and researchers hope to translate this technology for human use.


Giovanna Paolone and colleagues, based primarily at EARA member, the University of Ferrara, Italy, and working with Gloriana Therapeutics, attempted to suppress epileptic activity using the protein GDNF.


While cutting seizure rates in male rats the device also improved rats' anxiety-like symptoms and their performance in cognition-testing tasks.

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