As the end of the year approaches, we reflect on the remarkable scientific discoveries made in 2025 across various fields, ensuring that all methodologies, including the use of animals, are integrated into the most contemporary biomedical research. 

A new study from Greece has found that animals are increasingly affected by non-communicable diseases (NCDs), such as cancer, diabetes and obesity – conditions that are also increasingly common in humans. Understanding the shared factors contributing to these diseases could help improve both veterinary and human health. 

A prominent gene therapy company has announced a groundbreaking therapy for Huntington’s disease that slowed disease progression by 75% in human clinical trials.

Researchers in Germany have found, in a study using mice and humans, that loss of the sense of smell can be one of the earliest signs of Alzheimer’s, before cognitive impairment. 

Researchers in Israel are preparing to test the first-ever implantation of patients’ own spinal cord cells to restore mobility in paralysed individuals — a breakthrough made possible by foundational experiments in mice. 

Spanish researchers captured the first video of a human embryo implanting in a uterus, which could help improve understanding of the natural process and improve fertility and assisted reproduction techniques. 

Research from the United States shows that semaglutide, the active component of weight loss drugs Wegovy and Ozempic, slowed biological...

Research from the US in ferrets shows that previous infections with seasonal flu viruses or vaccinations might offer some limited...

A new treatment, developed in Canada, could offer a stem cell treatment option for blood cancer patients unable to find a matching donor.