Researchers in the US have generated lab-grown human heart and liver organoids that form their own blood vessels, overcoming a major limitation in organoid development. 

Research from Sweden has revealed how aggressive Shigella bacteria cause severe gut infections by using organoids to study the infection process. 

A feature on “The Scientist”, by Hannah Thomasy, provides an overview of the recent plans announced by the FDA to phase out animal testing in drug development by replacing animals with New Approach Methodologies (NAMs), such as organoids and organs-on-a-chip systems, as well as computational approaches, including AI. 

Researchers in Germany have developed a 3D culture of pancreatic cells to better replicate the ones found in humans, contributing to diabetes research. 

A new feature by EARA Swiss Ambassador, Rémi Cartier, examines the current use and limitations of “organoids” that are becoming a widely used tool in biomedical research but emphasises they cannot yet replace animal studies. 

Researchers from Austria and India have developed an innovative 3D-printed skin model capable of evaluating the absorption and safety of...

Using computer modelling and animal studies researchers in Germany have found that rhythmic patterns in brain cell circuits play a...

Researchers in Germany have developed a heart organoid that is capable of producing blood, to improve the study of heart development and...

EARA has published a feature looking at the current status of alternative methods to animals in safety testing, and exploring what this...

Research from Switzerland has led to the development of a 3D lab model  of human lip cells, replacing the need to use mice  in the study...

Following a change in US policy, a test that uses the blood of horseshoe crabs can now be replaced by a synthetic alternative. The blood...

Researchers in France have used ‘organ-on-chip’ technology to shed light on the effectiveness of booster vaccines for Covid-19 and other...

Using 3D brain organoids, researchers have linked a gene with Huntington’s disease for the first time, which may provide a new target for...

Organoids derived from people with diabetes have shed light on how the condition damages blood vessels, in a study using stem cells....