Gene edited mice to improve research


The Mary Lyon Centre at MRC Harwell, UK, is looking to fund projects to develop models of genetically altered mice for use in biomedical research.


Harwell’s Genome Editing Mice for Medicine (GEMM) has published a series of case studies on previously successful applicants.


For instance, the mouse model of Professor Nick Greene of Great Ormond Street Institute of Child Health, in London, has led to a better understanding of the rare metabolic disease Non-Ketotic Hyperglycinemia (NKH), including routes for future therapy.


To date GEMM has funded more than 80 mouse models that have been made available to researchers to help them understand diseases and conditions, including Parkinson’s and diabetes.


GEMM is accepting applications until 2 December, 2022.


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