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New target in Alzheimer’s

A team of Spanish scientists has identified the role of an enzyme which reduces inflammation in the brain.

The study, published in the journal Neurotherapeutics, showed that inhibition of an enzyme called sEH – a biological molecule that speeds up chemical reactions – to decrease its activity in the brains of mice reduced the inflammation, and neuronal damage that causes Alzheimer’s disease.

This new therapeutic strategy “could be an appropriate, effective and safe therapy in pathologies that cause inflammation," said Santiago Vázquez (pictured), of the team from the University of Barcelona, which worked in collaboration with EARA member August Pi i Sunyer Biomedical Research Institute (IDIBAPS).


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