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Testing leading vaccine and drug candidates Before treatments to either prevent or treat Covid-19 are This may be particularly the case with a Covid-19 vaccination as experience with SARS, a similar coronavirus Rhesus macaques have also been used in safety and efficacy testing of Sinovac’s PicOVacc Covid-19 vaccine Fort Detrick - Preclinical vaccine testing. Beth Israel Deaconess Medical Center, Israel- DNA vaccine protection against Covid-19 in rhesus macaques

Scientists have developed an effective vaccine against malaria, using the mRNA technology first seen in the successful Covid-19 vaccines. The vaccine uses mRNA to teach the human body how to make a small portion of the parasite that causes results published by the Walter Reed Army Institute of Research, USA, the team showed that mice given the vaccine

The MEPs called for a shift away from the use of animal models in Covid-19 research. rebuttal, sent to the Commissioners and the EMA, EARA stressed the importance of animal models in Covid Both the Commission and the EMA replies to the MEPs outlined that they were tackling Covid-19 with scientific

Wereldwijde toezichthouders hebben de resultaten van een workshop over de ontwikkeling van COVID-19-vaccins tegen COVID-19 de ziekte zouden kunnen versterken. -19-vaccin voor mensen. De voordelen zijn vrij duidelijk: levens redden door zo snel mogelijk over een vaccin tegen COVID-19 Onderzoek wijst uit dat er bij vaccins tegen coronavirussen een risico bestaat tot zogenaamd ‘vaccin

Scientists at Rutgers Cancer Institute of New Jersey, USA, have identified a new way to deliver a vaccine researchers using mice and monkeys, developed an aerosol system using small particles which deliver the vaccine The team hope that the inhalation delivery method could be especially relevant for vaccination against diseases which affect the lungs, such as Covid-19, as it ensures the vaccine reaches the relevant organ “This translational strategy potentially enables more effective delivery of therapeutics or vaccines

The findings in Nature Medicine, show the virus that causes Covid-19 might infect the intestinal tract

EARA has publicly challenged the false claims, about Covid-19 vaccine testing, made in the media by animal Joanna Lumley which asserted that human trials were sometimes conducted ahead of animal testing for Covid -19 vaccines. resulted in some testing on humans and animals being conducted at the same time, such as with the Moderna vaccine -19 vaccine development – other fact-checking pieces also confirmed the stories were fake, see Reuters

EARA members, from Denmark and France, have demonstrated how minipigs can help develop and test new vaccines explained how the minipig provides a good model for studying the long-term effects of the pertussis vaccine Minipigs were vaccinated at a similar schedule to humans, and the immune cells and antibodies produced Asked about the potential of using minipigs as an alternative to non-human primates in testing other vaccines

now needed, providing compelling stories about the success of animal research, such as in developing Covid vaccines, as well as the facts and figures about its benefits.

Animal experiments, cell studies and computational models are being used by researchers around the world to find the origins of the current pandemic. An article in Nature looks at the various studies underway that may help to understand how the coronavirus develops, what other animal species are susceptible to infection and the likely pattern of mutation in the virus. Currently a team at the CAS Institute of Microbiology, Beijing, China, plans to introduce RATG13 – a genome found in bats that is almost identical to SARS-CoV-2 – into bats, cats, monkeys and pigs, to study mutations. Another group from the University of Hong Kong found that the virus replicates well in organoids - 3D tissue culture that mimics in vivo organs - grown from intestinal stem cells of Chinese horseshoe bats. Meanwhile, a study at University College London, UK, modelled the structure of ACE2 - the receptor that allows the virus to infect and destroy our cells - from more than 215 vertebrates. This found that the receptor in sheep, chimpanzees and gorillas, engages with the protein on the surface of the virus, which suggests that these animals might be susceptible to infection.

Researchers at the Institut Pasteur, Paris, France, have developed a successful vaccine to treat severe In collaboration with NEOVACS, a French biotechnology company, the team created a vaccine that generates The findings, published in Nature Communications, show the new vaccine could create long-term protection

Fears of domestic and farm animals being infected by Covid-19 and in turn spreading it further, has led Research from China has shown Covid-19 to not be very infectious in dogs, pigs, chickens and ducks, but ferrets and cats could be readily infected, however there is no evidence that humans can acquire Covid In a Q&A on Covid-19, the World Organisation for Animal Health said: “Currently, there is no evidence to suggest that animals infected by humans are playing a role in the spread of Covid-19.”